Adipotide (also called FTPP) is an experimental “fat-targeting” peptide designed to selectively destroy the blood vessels that supply fat tissue.
It is not FDA-approved and has only been studied in animals and limited early human research.
Here’s what it does in the body:
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1. Targets Fat Tissue Blood Vessels
Adipotide is a proapoptotic peptide linked to a targeting sequence that binds to receptors found primarily on blood vessels feeding white adipose tissue.
Once it binds:
•It enters the endothelial cells of fat blood vessels
•Disrupts mitochondrial function
•Triggers apoptosis (cell death)
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2. Causes Fat Tissue Shrinkage
When fat tissue loses its blood supply:
•Fat cells become stressed
•Fat mass shrinks
•Overall body weight decreases
In primate studies, this led to:
•Significant fat loss
•Reduced abdominal fat
•Improved insulin sensitivity
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3. Improves Metabolic Markers (In Studies)
Animal studies showed:
•Lower fasting insulin
•Improved glucose control
•Reduced waist circumference
Adipotide is a fat-targeting peptide that:
•Shrinks white fat by destroying its blood supply
•Showed promising weight loss in animals